Reason that some patients get cured of the type-two diabetes after gastric bypass might have been elaborated by the researchers of US.
Their study of animal showed that bypassing stomach made intestines work more harder, use increased amount of energy and also keep levels of blood sugar under control.
The researchers hope that their findings which are published in journal Science, would lead to decreased invasive treatments meant for this condition.
It is also said that healthy lifestyle is best way of avoiding this disease.
Diabetes of type-2, which is most of the times result of some bad diet as well as little exercise, happens to be one globally growing problem.
It leaves the people incapable of controlling amount of blood sugar and could culminate in limb loss, heart disease and blindness.
This condition could be managed by insulin injections.
The researchers at the Boston Children’s Hospital, located in US, were trying to investigate how any surgery type for weight loss affected diabetes.
According to Dr Nicholas Stylopoulos, gastric bypass was the most useful procedure for weight loss, though it cures diabetes also and he wishes that they knew how the procedure worked so that new treatments, which are surgery-free, could be developed.
Weight loss can itself reduce symptoms of the diabetes of type-2, however, this condition could be cured seemingly before any of the pounds are shed.
Challenge for the researchers was figuring out where extra sugar that should be reaching the blood actually, was going.
The researchers performed an operation on rats of connecting entrance to stomach with small intestine and essentially bypassing stomach.
Animals then were scanned and route of the meals they took was traced while they travelled through body.
Dr Stylopoulos told that surprisingly, it was found that the sugar was getting used by the intestines – it was supposed to work quite harder when the stomach is bypassed.
Also, the intestines had to pass through some of the internal rebuilding like part of transition, which used energy also.
This study showed boost in intestines’ needs for energy that could account 64% of change in the blood levels of sugar. Remaining effect seems to be due to hormonal changes and weight loss.
Their plan constitutes coming up with some ways of activating intestines in order to produce same effect, though, without an operation.
According to Dr Stylopoulos, most of the patients prefer something that is equally effective, though, less invasive.
Head of the research at the Diabetes UK, Dr Matthew Hobbs, said that this work gave more details regarding what happens at the time surgery of gastric bypass is used in treating type-two diabetes.
He also added,
“While we would welcome any advances in this area, it is clear any new treatments are many years away. What we know now is that avoiding type-2 diabetes by maintaining a healthy balanced diet and being physically active is really important.”